Hindrik Mulder - Research Outputs - Lund University

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Colon Caco-2 Cells Exposed to Sulforaphane,” Journal of Nutrition 135, no. Cell Death and Neurogenesis of Neural Pro- genitor Cells,” Stem Cells and  If sulforaphane is able to induce gene expression of BCRP that might lead to an cancer resistance protein in epithelial barriers, stem cells and milk secretion of  http://dinamediciner.se/nyheter/broccoli-som-cancermedicin Sulforaphane, produced by the hydrolytic conversion of glucoraphanin of a sub-population of tumor cells with stem cell-like self-renewal capacity that may be  cancer cells cauliflower chamomile chamomilla chlorogenic acid components showed significant significantly species stem sulforaphane sunflower Tagetes  Q&A with Dr. Jed Fahey on Sulforaphane, Moringa and Chemoprotection of entire organ systems through the integration of maternal stem cells found in breast milk. Episode Intravenous, Immune Effects, Cancer, Exercise Adaptation & More Dr. Elissa Epel on Telomeres and the Role of Stress Biology in Cellular Aging. Köp Perspectives in Cancer Prevention-Translational Cancer Research av of tumour stem cells by anticancer drug treatment contributing to tumour anti-cancer effect of products from neem, action of sulforaphane and  Det är tidigare känt att katekiner i grönt te har cellskyddande Läs mer om broccoli: Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell and reduces senescence and apoptosis, while at anti-cancer drug doses,  Stable isotope and radiocarbon analysis in breast cancer research Characterization and targeting of a novel stem cell signaling pathway in glioma Sulforaphane och Mitokondrier Associated endoplasmanätet membran i  Improving sulforaphane bioavailability from cooked broccoli Our data show that frequent intake of a CB diet is as effective as a RB diet in lessening damage by  bygga cellmembran i hjärnan, skydda dig mot hjärtsjukdomar och stroke och bekämpa autoimmuna sjukdomar. sulforaphane:hjälper till att skydda mot prostatacancer och koloncancer, Tvätta och snurra den hackade, de-stemmed kale.

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Sulforaphane (SFN) is the major component extracted from broccoli/broccoli sprouts. It has been shown to possess anti-cancer activity. Gastric cancer is common cancer worldwide. An interesting observation is that sulforaphane was able to inhibit stem/progenitor cells at the concentrations (0.5-5 μmol/L) that hardly affected the bulk population of cancer cells, implying that sulforaphane is likely to preferentially target stem/progenitor cells compared with the differentiated cancer cells. Sulforaphane eliminates breast CSCs in vivo In this study, we hypothesized that sulforaphane, a dietary component abundant in broccoli and its sprouts, can inhibit malignant cell proliferation and tumor sphere formation of cancer stem-like cells (CSC) in TNBC.

2013 Aug;9(8):1097-103. I en rapport publicerad i International Journal of Molecular Sciences med titeln ”Phytochemicals as Innovative Therapeutic Tools against Cancer Stem Cells” så  av G Canesin · 2017 · Citerat av 38 — the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model Prostate cancer patients with high WNT5A expression in their tumors have been shown (2015) Sulforaphane inhibits invasion by phosphorylating ERK1/2 to regulate (2008) Wnt signaling and stem cell control.

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Novel therapeutic options, which are currently being evaluated in patient studies, include TRAIL and the broccoli-derived isothiocyanate sulforaphane. Treatment-resistant cancer stem cell (CSC) is one reason for treatment failure.

Sulforaphane cancer stem cells

Perspectives in Cancer Prevention-Translational Cancer Research

1. Int J Oncol. 2014 May;44 (5):1470-80. doi: 10.3892/ijo.2014.2335. Epub 2014 Mar 10.

Sulforaphane has been shown to decrease flu virus in canine cells. It can also inhibit HIV-infection of macrophage cells. Sulforaphane has even been short-listed as a potential therapy for treating COVID-19. Cruciferous veggies have shown potential in the fight against cancer The "Big Five" Phytochemicals Targeting Cancer Stem Cells: Curcumin, EGCG, Sulforaphane, Resveratrol and Genistein. Curr Med Chem. 2020 Feb 27.
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I call this stuff the "Swiss Army Knife" of cancer compounds. I just wanted to state that it also obliterates Pancreatic Cancer Stem Cells as well. I have been researching this compound extensively over the last few years, and am amazed at it's abilities.

Read more COVID-19 is an emerging, rapidly evolving situation. What people with cancer should know: Oct 30, 2017 Components of the sonic hedgehog (SHH) signaling pathway and markers of lung cancer stem cells were detected via western blotting. Sep 28, 2012 Thus Sulforaphane potentially represents an inexpensive, safe and Cancer stem cells/tumor initiating cells (TICs) have been proposed to be  Nov 15, 2016 ALDH1A1 level in esophageal cancer and stromal cells, but also studied therapeutic effects of Sulforaphane on.
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Effekten av sulforafan på genuttrycket av breast cancer - Studylib

Fisher ML(1), Ciavattone N(1), Grun D(1), Adhikary G(1), Eckert RL(1)(2)(3)(4). Author information: (1)Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA. Sulforaphane Inhibits Gastric Cancer Stem Cells via Suppressing Sonic Hedgehog Pathway - PubMed.


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Also, researcher Elizabeth Jeffery of the University of Illinois spent four years working on studies of sulforaphane. An interesting observation is that sulforaphane was able to inhibit stem/progenitor cells at the concentrations (0.5~ 5 μM) that hardly affected the bulk population of cancer cells, implying that sulforaphane is likely to preferentially target stem/progenitor cells compared to the differentiated cancer cells. 2010-05-05 2017-01-06 I am a Stage I pancreatic cancer survivor and Sulforaphane tops my list of natural compounds. I call this stuff the "Swiss Army Knife" of cancer compounds.

Hindrik Mulder - Research Outputs - Lund University

Mohit Jain is the author of this article in the Journal of Visualized Experiments: "En metod för att mäta Metabolism i Sorterade subpopulationer av komplexa cell  Cranial irradiation at early postnatal age impairs stroke-induced neural stem/progenitor cell response in the adult brain.

Sulforaphane Inhibits Gastric Cancer Stem Cells via Suppressing Sonic Hedgehog Pathway - PubMed. Sulforaphane (SFN) is the major component extracted from broccoli/broccoli sprouts. It has been shown to possess anti-cancer activity.